1. | IN-VIVO NEUROBEHAVIORAL AND BIOCHEMICAL EVALUATION OF TINOSPORA CORDIFOLIA ON RATS |
| K.Sivaji*, M.Sneha, K.Sireesha, CH.Satya Surya, N.Naga Lakshmi, V.Vidya, K.Asha, Y.Ganga Sireesha |
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Article Type:Research Article
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No of Download=125 |
Pages (1128-1132) |
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Main objective of evaluating the alcoholic leaf extract of Tinospora cordifolia. For anti Alzheimer’s activity usingaluminum chloride induced neurotoxicity model in rats as an experimental animal. Chronic administration ofaluminium chloride significantly raised MDA and nitrite concentration, depleted reduced GSH, and superoxidedismutase, and catalase activities in the whole brain compared to naive rats (p < 0.05). However, chronic ELTC(250and 500 mg/kg administration to the rats significantly attenuated oxidative damage (as indicated by reductions inMDA, nitrite concentration and reduced GSH, and decreased superoxide dismutase, and catalase activities) ascompared to control rats.
Key Words: Tinospora cordifolia, anti Alzheimer’s activity, aluminium chloride induced neurotoxicity
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2. | EVALUATION OF MEDICINAL DRUGS ON IN- VIVO ANTI OXIDANT AND NEUROBEHAVIORAL IN RATS |
| K.Sivaji*, T.Vijayendra, K.Srujan Kumar, M.Abhinay, A.D.N.K.Valli, R.Dineesha,N.Yashwanth, R.Tejalakshmi |
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Article Type:Research Article
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No of Download=130 |
Pages (1133-1136) |
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To study the comparative and combinational effects of Aspirin and N-Acetylcysteine on global cerebral ischemicreperfusion injury. The combination of ASP and NAC improved neurological outcome compared with NAC and ASPgiven alone but the difference is not significant so there is no significant additive effect was observed. Theimprovement in anti-oxidant potential of combinational treatment group shown significant difference with individualtreatment groups.Key Words: comparative and combinational effects, neurobehavioral
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3. | IN-VITRO ANTIOXIDANT AND ANTICANCER POTENTIAL OF ETHANOLIC EXTRACT OF SOLANUM SURATTENSE |
| A.Sravya*, R.V.Pavan Kumar, A.B.Yamini, A.N.Vara Lakshmi, B.Bhavana, K.Venkateswarlu,V.Rama Satya, M.Ruth |
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Article Type:Research Article
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No of Download=128 |
Pages (1137-1139) |
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To explore the preliminary phytochemical screening, in-vitropharmacological evaluation ofantioxidant activityandanticancer potential of ethanolicextracts ofSolanum surattense.ethanolic extract of the Solanum surattense, a widelyused medicinal herb in traditional medicine, demonstrated potential, dose dependent, cytotoxic activity against HeLacancer cell linesKey Words:Solanum surattense, cytotoxic activity, antioxidant activity
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4. | IN-VITRO AND IN-VIVO ANTI-INFLAMMATORY ACTIVITY OF ETHANOLIC EXTRACT OF BOSWELLIA SERRATA |
| A.D.S.Sai Lakshmi*, M.Sirisha, K.Vidya, G.Nireekshna Rao, K.Jnanendra Kumar, CH.Parvathi,D.T.S.S.V.Prasad, T.Praveen |
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Article Type:Research Article
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No of Download=126 |
Pages (1140-1143) |
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Aim is to explore the in-vitro and in-vivo pharmacological evaluation of antiinflammatory potential of ethanolic leafextracts of Boswellia serrata. In-vitroHRBC membrane stabilization and in-vivoCotton pelletgranuloma methoddemonstrates the dose dependent ant-inflammatory activity.Key Words:ant-inflammatory activity, Boswellia serrata, Cotton pelletgranuloma
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5. | ANTI-SPASMODIC EFFECTS OF TRADITIONAL MEDICINAL PLANT ON EXPERIMENTAL RABBIT MODEL |
| K.Anusha Jasmine*, M.Neelima Durga, K.Syam, K.Hima Bindu, K.Sowjanya, J.Aishwarya, K.Naga Lakshmi |
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Article Type:Research Article
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No of Download=126 |
Pages (1144-1146) |
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Present study has been under taken with main objective of evaluating the aqueous extract of flowers of Muntingiacalabura for antispasmodic activity using rabbit as an experimental animal model. In conclusion, the findings suggestthat Muntingia calabura has antispasmodic activities which are mediated possibly through blockade of calciumchannels as well as release of calcium from intracellular stores.Key Words: Muntingia calabura, antispasmodic activity
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6. | Pharmacogenomic Testing in Community Pharmacies: Ethical Considerations |
| Malini S |
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Article Type:Research Article
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No of Download=142 |
Pages (1147-1149) |
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Pharmacists are among the most accessible healthcare professionals, and they are well-positioned to lead innovativeclinical efforts like pharmacogenomics (PGx) services. It's important to comprehend pharmacists' and patients'perspectives of PGx, as well as the potential impediments to incorporating it into ordinary clinical practice.Institutions interested in launching a PGx programme should devise ways to address difficulties such as educationalknowledge gaps, informatics, and reimbursement issues. The criteria for delivering complete genetic data for tailoredmedication therapy are strong institutional support, well-defined goals, standardised methods, and ways to educatedoctors and patients.Key Words: Community Pharmacist, Pharmacogenomics, Genetic testing, Pharmacogenetics.
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